Australian Journal of Chemistry Australian Journal of Chemistry Society
An international journal for chemical science
Table of Contents
Australian Journal of Chemistry

Australian Journal of Chemistry

Volume 66 Number 1 2013

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This review highlights recent progresses in the self-assembly of complex organic molecular architectures that are enabled by dynamic imine chemistry, including molecular containers with defined geometry and size, mechanically interlocked molecules, and extended frameworks and polymers, from building blocks with preprogrammed steric and electronic information.

CH12347Synthesis and Self-Assembly of a Peptide–Amphiphile as a Drug Delivery Vehicle

Soo Jung Son, Margaret A. Brimble, Sunghyun Yang, Paul W. R. Harris, Tom Reddingius, Benjamin W. Muir, Oliver E. Hutt, Lynne Waddington, Jian Guan and G. Paul Savage
pp. 23-29
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A peptide–amphiphile comprised of the neuroprotective tripeptide motif glycyl-prolyl-glutamic acid linked to a hydrophobic moiety self-assembles into functional nanoparticles that display short range order and can be dispersed as micrometre-sized particles.

CH12393Natural Product-Inspired Pyranonaphthoquinone Inhibitors of Indoleamine 2,3-Dioxygenase-1 (IDO-1)

David J. A. Bridewell, Jonathan Sperry, Jason R. Smith, Priambudi Kosim-Satyaputra, Lai-Ming Ching, Joanne F. Jamie and Margaret A. Brimble
pp. 40-49
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Pyranonaphthoquinones exhibit low micromolar inhibition of indoleamine 2,3-dioxygenase-1 (IDO-1). These inhibitors retain activity against the enzyme in a cellular context with an approximate one-log loss of dose potency against IDO-1 in cells. Triazole 8 shows good inhibition of IDO-1 along with little loss of cell viability at low drug concentrations.

CH12308The Hydrogen-Bonding Interactions between 1-Ethyl-3-Methylimidazolium Lactate Ionic Liquid and Methanol

Hongyan He, Hui Chen, Yanzhen Zheng, Xiaochun Zhang, Xiaoqian Yao, Zhiwu Yu and Suojiang Zhang
pp. 50-59
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The hydrogen-bonding properties of binary systems consisting of a representative lactate-based ionic liquid (IL) 1-ethyl-3-methylimidazolium lactate ([EMIM][LAC]) and a cosolvent, methanol, have been studied by the combined application of FTIR spectroscopy and DFT calculations over the entire concentration.

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Poly(2,6-dimethyl-1,4-phenyleneoxide) (PPO) was depolymerized by adding phenols under oxidative conditions in green solvents. PPO depolymerized to oligomeric products in a faster process in water. In addition to water, an ionic liquid mixture containing the 1-ethyl-3-methylimidazolium cation and a mixture of alkylbenzenesulfonate with xylene sulfonate anion was used for the depolymerization of PPO.

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Three new 2D copper(ii) complexes were hydrothermally synthesized using a flexible bis(pyridylamide) ligand L as the main ligand and three polycarboxylates as the auxiliary ligands. The fluorescent properties of the three compounds and the electrochemical behaviour of a compound 2-modified carbon paste electrode (2-CPE) were studied.

CH12336Simple Method and Materials to Target Co(II)-Dy(III) Multi-Nuclear Magnetic Compounds and Single Molecule Magnets (SMMs): Synthesis, Structure, and Magnetic Studies

Yan Zhu, Feng Luo, Xue-Feng Feng, Zhen-Wei Liao, Yu-Mei Song, Hai-Xiao Huang, Xiao-Zhao Tian, Gong-Ming Sun and Ming-Biao Luo
pp. 75-83
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We present here a simple method and materials to target Co(ii)-Dy(iii) multi-nuclear magnetic compounds. As a result, seven discrete Co(ii)-Dy(iii) compounds with di-, tri-, and tetranuclear structures are prepared.

CH12326Synthesis, Antimicrobial Activity, and Molecular Docking Study of Some Novel Cyclophanes with Imino Intra-Annular Functionality

Perumal Rajakumar, Ramar Padmanabhan, Chandrasekaran Ramprasath, Narayanasamy Mathivanan, Vaidhyanathan Silambarasan and Devadasan Velmurugan
pp. 84-92
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The synthesis and structural characterisation of novel imino cyclophanes incorporating various spacer units is described. Comparable antibacterial activity against Gram positive (Bacillus subtillus, Staphylococcus aureus) and Gram negative (Escherchia coli, Klebsiella pneumonia) bacterial strains is exhibited along with good antifungal activity against human pathogenic fungus, Candida albicans.

CH12356Solid-Phase Organic Synthesis of Dexoxadrol Analogues

Michael Sax and Bernhard Wünsch
pp. 93-97
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A solid-phase organic synthesis of dexoxadrol analogues with a carbonyl moiety in the 4-position of the piperidine ring has been established. Key steps of the synthesis include an imino-Diels–Alder reaction with Danishefsky’s diene and a conjugate reduction of the double bond using LiBHEt3 in the presence of a Lewis acid.

CH12377Carboxylate-Bridged Dinuclear Dy2 Single-Molecule Magnets: Synthesis, Structure, and Magnetic Studies

Yu-mei Song, Feng Luo, Yan Zhu, Xiao-zhao Tian and Gong-ming Sun
pp. 98-104
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We demonstrate here a simple and effective method to access 4f single-molecule magnets (SMM). Further, the relatively fine-tuned SMM properties of compounds 13, possibly controlled by the terminal ligands around the metal ions, are highlighted.

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A photochard can be utilized in the field, to give an indicatvie concentration of pentachlorophenol (ppm) in natural water samples. A precise concentration can be determined through the use of UV/Vis spectroscopy (either in the field or laboratory), in the range of 2 ppb–1000 ppm, depending on sample treatment.

CH12375A Simple and Sensitive Colorimetric Detection of Silver Ions Based on Cationic Polymer-Directed AuNPs Aggregation

Faze Wang, Yuangen Wu, Shenshan Zhan, Lan He, Wenting Zhi, Xiaoxuan Zhou and Pei Zhou
pp. 113-118
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This paper describes a simple and sensitive colorimetric sensor employing single-stranded DNA (ssDNA) ligand, cationic polymer, and gold nanoparticles (AuNPs) to detect silver ions. The concentration of Ag+ can be determined visually. The method is simple, effective, and convenient and can in principle be used to detect other metal ions or small molecules.

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