Synthesis of ω-Hydroxy Quaternary Ammonium Bolaform Surfactants
Tim W. Davey and Alan R. Hayman
Australian Journal of Chemistry
51(7) 581 - 586
AbstractSeveral members of a novel class of w-substituted asymmetric bolaform surfactants have been synthesized in order to investigate their surfactant and biological properties. The ω-hydroxy trialkylammonium and pyridinium surfactants have significant antimicrobial and antifungal activity relative to their conventional analogues. For conventional quaternary ammonium alkyl surfactants, increasing the hydrocarbon chain length causes a decrease in the surfactant monomer solubility and a corresponding decrease in the biological activity. No such trend is observed for the ω-hydroxy quaternary ammonium bromide series.
© CSIRO 1998