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Australian Journal of Chemistry Australian Journal of Chemistry Society
An international journal for chemical science
RESEARCH ARTICLE

The Synthesis of Almazoles A and B

Jabbar Khalafy, Rolf H. Prager and Craig M. Williams

Australian Journal of Chemistry 52(1) 31 - 36
Published: 1999

Abstract

Almazoles A (1) and B (2) are formed in seven steps from phenylalanine without any racemization. The key step is the N-acylation of the isoxazol-5(2H)-one (5) with the phthalimide-protected amino acid, and photolysis of the product at 300 nm in acetone.

https://doi.org/10.1071/C98093

© CSIRO 1999

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