Transition metal complexes of thiabendazole

Abstract

Complexes of thiabendazole with transition metals (Co²⁺, Cu²⁺, Fe²⁺, Fe³⁺, Mn²⁺, Ni²⁺, and Zn²⁺) containing one, two, or three molecules of ligand per metal ion are described. Their spectra and magnetic moments are reported. In general, the complexes are insoluble or only slightly soluble in water or most organic solvents. Only complexes of metal chlorides are sufficiently soluble in methanol to show electrical conductivity. It is suggested that most of the insoluble complexes are of polymeric character.   The anthelmintic activity of all complexes is only slightly higher than that of thiabendazole.