Australian Journal of Chemistry Australian Journal of Chemistry Society
An international journal for chemical science

β-Cyclodextrin Inclusion of Adamantane Derivatives in Solution

R Palepu and VC Reinsborough

Australian Journal of Chemistry 43(12) 2119 - 2123
Published: 1990


The binding constants for β- cyclodextrin inclusion in aqueous solution of a few simple adamantane salts have been determined by a conductimetric technique at 25°C over the pH range 4-10. Binding was largely dictated by the closeness of fit of the adamantyl moiety within the β- cyclodextrin cavity with the charge on the substituent group playing a minor role. The strongest binding occurred when the charge was neutralized by protonation or deprotonation.

© CSIRO 1990

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