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Synthesis and Preliminary Pharmacological Evaluation of 4´-Arylmethyl Analogues of Clozapine. I. The Effect of Aromatic Substituents

B. Capuano, I. T. Crosby, E. J. Lloyd and D. A. Taylor
55(9) pp.565 - 576


25 articles found in Crossref database.

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Capuano Ben, Crosby Ian, Lim Sean, Lloyd Edward, Yuriev Elizabeth
Molbank. 2006 2006(2). p.M475
JL13 has clozapine-like actions on thermoregulatory cutaneous blood flow in rats: Involvement of serotonin 5-HT1A and 5-HT2A receptor mechanisms
Capuano B., Crosby I.T., McRobb F.M., Taylor D.A., Vom A., Blessing W.W.
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 2010 34(1). p.136
Synthesis and biological evaluation of 5,10-dihydro-11 H -dibenzo[ b,e ][1,4]diazepin-11-one structural derivatives as anti-cancer and apoptosis inducing agents
Praveen Kumar Chintakunta, Reddy T. Srinivasa, Mainkar Prathama S., Bansal Vipul, Shukla Ravi, Chandrasekhar Srivari, Hügel Helmut M.
European Journal of Medicinal Chemistry. 2016 108 p.674
Synthesis of 8-chloro-11-(4-(3-(p-tolyloxy)propyl)piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine
Capuano Ben, Crosby Ian, Lim Sean, Lloyd Edward
Molbank. 2005 2005(6). p.M454
Simplified Procedure for General Synthesis of Monosubstituted Piperazines—From a Batch Reaction Vessel to a Flow (Microwave) Reactor
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Molecules. 2020 25(9). p.2168
Prefrontal cortex and reversion of atropine-induced disruption of the degraded contingency effect by antipsychotic agents and N-desmethylclozapine in rats
Carnicella Sebastien, Mongeot Alexandre, Bourguignon Jean-Jacques, Oberling Philippe
The International Journal of Neuropsychopharmacology. 2010 13(01). p.109
Direct and Indirect Drug Design Approaches for the Development of Novel Tricyclic Antipsychotics: Potential 5-HT2AAntagonist
Jadhav Mahantesh Namdev, Kokil Ganesh Rajendra, Harak Shilpa Sudhakar, Wagh Sanjay Baburao
Journal of Chemistry. 2013 2013 p.1
The Synthesis and Preliminary Pharmacological Evaluation of a Series of Substituted 4'-Phenoxypropyl Analogues of the Atypical Antipsychotic Clozapine
Capuano Ben, Crosby Ian T., McRobb Fiona M., Podloucka Anna, Taylor David A., Vom Amelia, Yuriev Elizabeth
Australian Journal of Chemistry. 2010 63(1). p.116
Aminimides as Potential CNS Acting Agents. II Design, Synthesis, and Receptor Binding of 4′-Arylalkyl Aminimide Analogues of Clozapine as Prospective Novel Antipsychotics
Capuano Ben, Crosby Ian T., Lloyd Edward J., Neve Juliette E., Taylor David A.
Australian Journal of Chemistry. 2008 61(1). p.5
N-[(3S)-1-Benzylpyrrolidin-3-yl]-(2-thienyl)benzamides: Human dopamine D4 ligands with high affinity for the 5-HT2A receptor
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Bioorganic & Medicinal Chemistry Letters. 2005 15(23). p.5253
Aminimides as Potential CNS Acting Agents. I. Design, Synthesis, and Receptor Binding of 4′-Aryl Aminimide Analogues of Clozapine as Prospective Novel Antipsychotics
Capuano Ben, Crosby Ian T., Lloyd Edward J., Neve Juliette E., Taylor David A.
Australian Journal of Chemistry. 2007 60(9). p.673
Asymmetric Hydrogenation Using Rhodium Complexes Generated from Mixtures of Monodentate Neutral and Anionic Phosphorus Ligands
Frank Dominik J., Franzke Axel, Pfaltz Andreas
Chemistry – A European Journal. 2013 19(7). p.2405
Exploration of (S)-3-aminopyrrolidine as a potentially interesting scaffold for discovery of novel Abl and PI3K dual inhibitors
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European Journal of Medicinal Chemistry. 2011 46(4). p.1404
The Application of the Schmidt Reaction and Beckmann Rearrangement to the Synthesis of Bicyclic Lactams: Some Mechanistic Considerations
Crosby Ian T., Shin James K., Capuano Ben
Australian Journal of Chemistry. 2010 63(2). p.211
8-Chloro-5-(4-phenethylpiperazin-1-yl)pyrido[2,3-b][1,5]benzoxazepine
Capuano Ben, Crosby Ian T., Forsyth Craig M., Lloyd Edward J., Vom Amelia, Yuriev Elizabeth
Acta Crystallographica Section E Structure Reports Online. 2008 64(10). p.o1865
Recent advances in dopamine D2 receptor ligands in the treatment of neuropsychiatric disorders
Juza Radomir, Musilek Kamil, Mezeiova Eva, Soukup Ondrej, Korabecny Jan
Medicinal Research Reviews. 2023 43(1). p.55
Synthesis of Benzyl 2-(4-(8-chloro-5H-dibenzo[b,e][1,4]diazepin-11-yl)piperazin-1-yl)acetate
Camerino Michelle, Capuano Ben, Crosby Ian, Lloyd Edward
Molbank. 2005 2005(6). p.M453
Design, Synthesis, and Cytotoxic Evaluation of Certain 7‐Chloro‐4‐(piperazin‐1‐yl)quinoline Derivatives as VEGFR‐II Inhibitors
Aboul‐Enein Mohamed Nabil, El‐Azzouny Aida M. Abd El‐Sattar, Ragab Fatma Abdel‐Fattah, Hamissa Mohamed Farouk
Archiv der Pharmazie. 2017 350(3-4).
Homobivalent Ligands of the Atypical Antipsychotic Clozapine: Design, Synthesis, and Pharmacological Evaluation
McRobb Fiona M., Crosby Ian T., Yuriev Elizabeth, Lane J. Robert, Capuano Ben
Journal of Medicinal Chemistry. 2012 55(4). p.1622
Synthesis and Preliminary Pharmacological Evaluation of 4′-Arylalkyl Analogues of Clozapine. IV. The Effects of Aromaticity and Isosteric Replacement
Capuano Ben, Crosby Ian T., Lloyd Edward J., Podloucka Anna, Taylor David A.
Australian Journal of Chemistry. 2008 61(12). p.930
Copper(I) Cyanide Networks: Synthesis, Structure, and Luminescence Behavior. Part 2. Piperazine Ligands and Hexamethylenetetramine
Lim Mi Jung, Murray Courtney A., Tronic Tristan A., deKrafft Kathryn E., Ley Amanda N., deButts Jordan C., Pike Robert D., Lu Haiyan, Patterson Howard H.
Inorganic Chemistry. 2008 47(15). p.6931
New hybrids of clozapine and haloperidol and their isosteric analogues: synthesis, X-ray crystallography, conformational analysis and preliminary pharmacological evaluation
Capuano Ben, Crosby Ian T., Forsyth Craig M., McRobb Fiona M., Moudretski Vladimir V., Taylor David A., Vom Amelia, Yuriev Elizabeth
Structural Chemistry. 2010 21(3). p.613
2-Chloro-1-[4-(2-fluorobenzyl)piperazin-1-yl]ethanone
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Acta Crystallographica Section E Structure Reports Online. 2011 67(3). p.o708
Modification of the clozapine structure by parallel synthesis
Su Jing, Tang Haiqun, McKittrick Brian A., Burnett Duane A., Zhang Hongtao, Smith-Torhan April, Fawzi Ahmad, Lachowicz Jean
Bioorganic & Medicinal Chemistry Letters. 2006 16(17). p.4548
Synthesis and Preliminary Pharmacological Evaluation of 4′-Arylalkyl Analogues of Clozapine. III. Replacement of the Tricyclic Nucleus with a Bicyclic Template
Capuano Ben, Crosby Ian T., Lloyd Edward J., Taylor David A.
Australian Journal of Chemistry. 2007 60(12). p.928

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