Register      Login
Australian Journal of Chemistry Australian Journal of Chemistry Society
An international journal for chemical science

Articles citing this paper

Thiol-Based ‘Click’ Chemistries in Polymer Synthesis and Modification

Andrew B. Lowe A B and M. Alyse Harvison A
+ Author Affiliations
- Author Affiliations

A Centre for Advanced Macromolecular Design (CAMD), School of Chemical Engineering, The University of New South Wales, Kensington, NSW 2052, Australia.

B Corresponding author. Email: a.lowe@unsw.edu.au




Professor Andrew B. Lowe holds B.Sc. (Hons) (1993), D.Phil. (1998), and D.Sc. (2009) degrees in Chemistry and Polymer Science from the University of Sussex, UK. After 10 years at the University of Southern Mississippi, first as a postdoctoral researcher and then as an Assistant and Associate Professor of Polymer Science and Engineering he moved, in May 2009, to the Centre for Advanced Macromolecular Design (CAMD) at the University of New South Wales, Australia, where he is currently a Professor of Macromolecular Science and Engineering. He has published approximately 90 papers, books, book chapters, encyclopedia articles, and abstracts. Professor Lowe’s current research interests broadly cover water-soluble and ‘smart’ copolymers, reversible addition–fragmentation chain transfer, ring-opening metathesis polymerization, and applications of thiol-based reactions in polymer synthesis and modification.



M. Alyse Harvison holds a B.Sc. degree (highest honours, 2008) in Chemistry from the University of Southern Mississippi, USA. During her undergraduate studies she was a recipient of the highly prestigious Coca-Cola National and Northrop Grumman Scholarships. In the fall of 2008 she joined the Ph.D. program in Polymer Science & Engineering at the University of Southern Mississippi, moving in August 2009 to continue her Ph.D. studies with Professor Lowe in CAMD where she is currently exploring the application of thiol-based chemistries as a means of selectively functionalizing and synthesizing novel (co)polymers.

Australian Journal of Chemistry 63(8) 1251-1266 https://doi.org/10.1071/CH10214
Submitted: 26 May 2010  Accepted: 30 June 2010   Published: 10 August 2010



69 articles found in Crossref database.

Antimicrobial equipment of poly(isoprene) applying thiol‐ene chemistry
Kienberger Julia, Noormofidi Nadja, Mühlbacher Inge, Klarholz Ingo, Harms Carsten, Slugovc Christian
Journal of Polymer Science Part A: Polymer Chemistry. 2012 50(11). p.2236
Thiol‐epoxy polymerization via an AB monomer: Synthetic access to high molecular weight poly(β‐hydroxythio‐ether)s
Binder Selmar, Gadwal Ikhlas, Bielmann Andreas, Khan Anzar
Journal of Polymer Science Part A: Polymer Chemistry. 2014 52(14). p.2040
The use of reversible addition fragmentation chain transfer polymerization for drug delivery systems
Gregory Andrew, Stenzel Martina H
Expert Opinion on Drug Delivery. 2011 8(2). p.237
Click Chemistry in Glycoscience (2013)
Witczak Zbigniew J.
Amphiphilic copolymers in biomedical applications: Synthesis routes and property control
Perin Francesca, Motta Antonella, Maniglio Devid
Materials Science and Engineering: C. 2021 123 p.111952
Recent Advances in Click Chemistry Applied to Dendrimer Synthesis
Arseneault Mathieu, Wafer Caroline, Morin Jean-François
Molecules. 2015 20(5). p.9263
Revisiting the Zincke disulfide reaction for the post-polymerization functionalization of unsaturated polyolefins
Dunst Andreas, Kienberger Julia, Slugovc Christian
Polymer. 2014 55(22). p.5557
Construction of antifouling fluorinated polymer brush via activators regenerated by electron transfer ATRP and thiol-epoxy click reaction
Chen Lin, Li Lin, Zhao Xu, Wang Shuangshuang, Li Yuchao, Li Guang, Ge Xiangcai, Wang Liping
Reactive and Functional Polymers. 2021 165 p.104974
Thiol–yne coupling: revisiting old concepts as a breakthrough for up-to-date applications
Massi Alessandro, Nanni Daniele
Organic & Biomolecular Chemistry. 2012 10(19). p.3791
Kinetics of multifunctional thiol-epoxy click reactions studied by differential scanning calorimetry: Effects of catalysis and functionality
Jin Kailong, Heath William H., Torkelson John M.
Polymer. 2015 81 p.70
Surface glycosylation of polymer membrane by thiol-yne click chemistry for affinity adsorption of lectin
Wang Cang, Ren Peng-Fei, Huang Xiao-Jun, Wu Jian, Xu Zhi-Kang
Chemical Communications. 2011 47(13). p.3930
Scalable ambient synthesis of water‐soluble poly(β‐hydroxythio‐ether)s
Hwang JiHyeon, Choe Youngson, Bang Joona, Khan Anzar
Journal of Polymer Science Part A: Polymer Chemistry. 2017 55(20). p.3381
Aliphatic–Aromatic Polyols by Thiol–Ene Reactions
Shrestha Maha L., Ionescu Mihail
Journal of Polymers and the Environment. 2018 26(6). p.2257
End‐functional polymers, thiocarbonylthio group removal/transformation and reversible addition–fragmentation–chain transfer (RAFT) polymerization
Moad Graeme, Rizzardo Ezio, Thang San H
Polymer International. 2011 60(1). p.9
Thermoresponsive (Co)polymers through Postpolymerization Modification of Poly(2-vinyl-4,4-dimethylazlactone)
Zhu Yicheng, Quek Jing Yang, Lowe Andrew B., Roth Peter J.
Macromolecules. 2013 46(16). p.6475
Composition optimization of a high-performance epoxy resin based on molecular dynamics and machine learning
Jin Kai, Luo Hao, Wang Ziyu, Wang Hao, Tao Jie
Materials & Design. 2020 194 p.108932
Dendrimer Based Nanoarchitectures in Diabetes Management: An Overview
Mishra Vijay, Yadav Nishika, Saraogi Gaurav K., Tambuwala Murtaza M., Giri Namita
Current Pharmaceutical Design. 2019 25(23). p.2569
Thio-Click Approach to Glycomimetics
Witczak Zbigniew J.
Phosphorus, Sulfur, and Silicon and the Related Elements. 2013 188(4). p.413
Novel α,α‐Bischolesteryl Functional (Co)Polymers: RAFT Radical Polymerization Synthesis and Preliminary Solution Characterization
Roth Peter J., Davis Thomas P., Lowe Andrew B.
Macromolecular Rapid Communications. 2014 35(8). p.813
Thiol-yne ‘click’/coupling chemistry and recent applications in polymer and materials synthesis and modification
Lowe Andrew B.
Polymer. 2014 55(22). p.5517
Preparation of emulsion-templated porous polymers using thiol–ene and thiol–yne chemistry
Lovelady Elaine, Kimmins Scott D., Wu Junjie, Cameron Neil R.
Polym. Chem.. 2011 2(3). p.559
Combining Ring‐Opening Metathesis Polymerization and Thiol‐Ene Coupling Chemistries: Facile Access to Novel Functional Linear and Nonlinear Macromolecules
Lowe Andrew B., Liu Meina, van Hensbergen Johannes Arend, Burford Robert P.
Macromolecular Rapid Communications. 2014 35(4). p.391
Catalytic Performance of Silica Supported Cinchona Alkaloids as Heterogeneous Catalysts for Asymmetric Michael Reaction
Zhao Wenshan, Zhang Yanli, Qu Chengke, Zhang Lei, Wang Jing, Cui Yuanchen
Catalysis Letters. 2014 144(10). p.1681
Transformation of the Bromine End Group into Thiol in (Meth)acrylic Polymers Synthesized by Atom Transfer Radical Polymerization
Liras M., García O., Quijada-Garrido I., París R.
Macromolecules. 2011 44(6). p.1335
Thiol‐X Chemistries in Polymer and Materials Science (2013)
Boutevin Bernard, Auvergne Remi, David Ghislain
Photocatalytic initiation of thiol–ene reactions: synthesis of thiomorpholin-3-ones
Keylor Mitchell H., Park James E., Wallentin Carl-Johan, Stephenson Corey R.J.
Tetrahedron. 2014 70(27-28). p.4264
Reversible addition–fragmentation chain transfer synthesis of amidine‐based, CO2‐responsive homo and AB diblock (Co)polymers comprised of histamine and their gas‐triggered self‐assembly in water
Quek Jing Yang, Roth Peter J., Evans Richard A., Davis Thomas P., Lowe Andrew B.
Journal of Polymer Science Part A: Polymer Chemistry. 2013 51(2). p.394
Thiol-Michael coupling chemistry: facile access to a library of functional exo-7-oxanorbornenes and their ring-opening metathesis (co)polymerization
Liu Meina, van Hensbergen Johannes, Burford Robert P., Lowe Andrew B.
Polymer Chemistry. 2012 3(6). p.1647
Photolatent base catalyzed Michael-addition and concomitant in situ graphene oxide reduction to obtain electrically and thermally conductive UV-cured composite
Gigot Arnaud, Morra Alessio, Castellino Micaela, Pirri Candido F., Mittal Vikas, Dietliker Kurt, Sangermano Marco
Polymer. 2017 108 p.251
Imprint Lithography with Degradable Elastomeric Polyanhydrides
Lou Qin, Shipp Devon A.
ACS Applied Materials & Interfaces. 2012 4(9). p.4457
Hybrid thiol-acrylate-epoxy polymer networks: Comparison of one-pot synthesis with sequential reactions and shape memory properties
Dhulst Elizabeth A., Heath William H., Torkelson John M.
Polymer. 2016 96 p.198
Addressing the mid-point of polymer chains for multiple functionalization purposes through sequential thiol–epoxy ‘click’ and esterification reactions
Gadwal Ikhlas, Eom Taejun, Hwang JiHyeon, Choe Youngson, Bang Joona, Khan Anzar
RSC Advances. 2017 7(32). p.19439
Effect of polymer grafting density on silica nanoparticle toxicity
Lin I-Chun, Liang Mingtao, Liu Tzu-Yu, Jia Zhongfan, Monteiro Michael J., Toth Istvan
Bioorganic & Medicinal Chemistry. 2012 20(23). p.6862
Nucleophilic thiol-Michael chemistry and hyperbranched (co)polymers: synthesis and ring-opening metathesis (co)polymerization of novel difunctional exo-7-oxanorbornenes with in situ inimer formation
Liu Meina, Tan Beng Hoon, Burford Robert P., Lowe Andrew B.
Polymer Chemistry. 2013 4(11). p.3300
RAFT-synthesized copolymers and conjugates designed for therapeutic delivery of siRNA
Smith DeeDee, Holley Andrew C., McCormick Charles L.
Polymer Chemistry. 2011 2(7). p.1428
One-Pot Endgroup-Modification of Hydrophobic RAFT Polymers with Cyclodextrin by Thiol-ene Chemistry and the Subsequent Formation of Dynamic Core–Shell Nanoparticles Using Supramolecular Host–Guest Chemistry
Yhaya Firdaus, Binauld Sandra, Callari Manuela, Stenzel Martina H.
Australian Journal of Chemistry. 2012 65(8). p.1095
Segmented Thermoplastic Polymers Synthesized by Thiol–Ene Click Chemistry: Examples of Thiol–Norbornene and Thiol–Maleimide Click Reactions
Jin Kailong, Leitsch Emily K., Chen Xi, Heath William H., Torkelson John M.
Macromolecules. 2018 51(10). p.3620
Thiol–ene “click” reactions and recent applications in polymer and materials synthesis: a first update
Lowe Andrew B.
Polym. Chem.. 2014 5(17). p.4820
Functional polymer particles via thiol–ene and thiol–yne suspension “click” polymerization
Durham Olivia Z., Norton Hannah R., Shipp Devon A.
RSC Advances. 2015 5(82). p.66757
Click-functionalized hydrogel design for mechanobiology investigations
Hui Erica, Sumey Jenna L., Caliari Steven R.
Molecular Systems Design & Engineering. 2021 6(9). p.670
Versatile Strategy for the Synthesis of Hyperbranched Poly(ε-caprolactone)s and Polypseudorotaxanes Thereof
Liu Wei, Dong Chang-Ming
Macromolecules. 2010 43(20). p.8447
RAFT polymerization of vinyl methacrylate and subsequent conjugation via enzymatic thiol‐ene chemistry
Yhaya Firdaus, Sutinah Arlingga, Gregory Andrew M., Liang Mingtao, Stenzel Martina H.
Journal of Polymer Science Part A: Polymer Chemistry. 2012 50(19). p.4085
Soft Actuators (2019)
Imran Abu Bin, Harun-Ur-Rashid Mohammad, Takeoka Yukikazu
Thiol‐X Chemistries in Polymer and Materials Science (2013)
Poetz Katie L., Durham Olivia Z., Shipp Devon A.
New polyols with isocyanuric structure by thiol-ene “click” chemistry reactions
Gupta Ram K, Ionescu M, Wan X, Radojcic D, Bilic N
Journal of Cellular Plastics. 2017 53(6). p.639
Radical Mediated Thiol-Ene Emulsion Polymerizations
Durham Olivia Z., Chapman Dana V., Krishnan Sitaraman, Shipp Devon A.
Macromolecules. 2017 50(3). p.775
Providing polyurethane foams with functionality: a kinetic comparison of different “click” and coupling reaction pathways
Nguyen Le-Thu T., Devroede Jan, Plasschaert Kathleen, Jonckheere Laura, Haucourt Nancy, Du Prez Filip E.
Polym. Chem.. 2013 4(5). p.1546
End Group Reactions of RAFT-Prepared (Co)Polymers
Harvison M. Alyse, Roth Peter J., Davis Thomas P., Lowe Andrew B.
Australian Journal of Chemistry. 2011 64(8). p.992
Preparation and Electric Property of Polysilsesquioxane Thin Films Incorporating Carbazole Groups
Watase Seiji, Fujisaki Daiki, Watanabe Mitsuru, Mitamura Koji, Nishioka Noboru, Matsukawa Kimihiro
Chemistry – A European Journal. 2014 20(40). p.12773
Functional Polymers by Post‐Polymerization Modification (2012)
Lowe Andrew B., Chan Justin W.
Efficient synthesis of multifunctional polymers via thiol–epoxy “click” chemistry
De Swati, Khan Anzar
Chemical Communications. 2012 48(25). p.3130
Polymer Microspheres Prepared by Water-Borne Thiol–Ene Suspension Photopolymerization
Durham Olivia Z, Krishnan Sitaraman, Shipp Devon A.
ACS Macro Letters. 2012 1(9). p.1134
Thiol‐alkyne Chemistry for the Preparation of Micelles with Glycopolymer Corona: Dendritic Surfaces versus Linear Glycopolymer in Their Ability to Bind to Lectins
Kumar Jatin, Bousquet Antoine, Stenzel Martina H.
Macromolecular Rapid Communications. 2011 32(20). p.1620
Functionalized vegetable oils as precursors for polymers by thiol-ene reaction
Ionescu Mihail, Radojčić Dragana, Wan Xianmei, Petrović Zoran S., Upshaw Thomas A.
European Polymer Journal. 2015 67 p.439
Reactions under the Click Chemistry Philosophy Employed in Supramolecular and Mechanostereochemical Systems
Fahrenbach Albert C., Stoddart J. Fraser
Chemistry – An Asian Journal. 2011 6(10). p.2660
Facile design of biomaterials by ‘click’ chemistry
Hvilsted Søren
Polymer International. 2012 61(4). p.485
Highly functional polyols from castor oil for rigid polyurethanes
Ionescu Mihail, Radojčić Dragana, Wan Xianmei, Shrestha Maha Laxmi, Petrović Zoran S., Upshaw Thomas A.
European Polymer Journal. 2016 84 p.736
A study on electro-optical properties of polymer dispersed liquid crystal films with thiol-isocyanate-ene ternary network prepared by nucleophile-initiated thiol-ene click reaction and thiol-isocyanate coupling reaction
He Taoyu, Yang Bo, Zhang Li, Shi Zhiqing, Gong Xinjian, Geng Pengfei, Gao Zhenwei, Wang Yinghan
Liquid Crystals. 2020 47(11). p.1624
Combining RAFT Radical Polymerization and Click/Highly Efficient Coupling Chemistries: A Powerful Strategy for the Preparation of Novel Materials
Harvison M. Alyse, Lowe Andrew B.
Macromolecular Rapid Communications. 2011 32(11). p.779
Heterofunctional RAFT‐derived PNIPAM via cascade trithiocarbonate removal and thiol‐yne coupling click reaction
Le Bohec Maël, Piogé Sandie, Pascual Sagrario, Fontaine Laurent
Journal of Polymer Science Part A: Polymer Chemistry. 2017 55(21). p.3597
Visible-light-activated selective synthesis of sulfoxides via thiol-ene/oxidation reaction cascade
Singh Manjula, Yadav Arvind K., Yadav Lal Dhar S., Singh R.K.P.
Tetrahedron Letters. 2018 59(5). p.450
Dendrimers: A versatile nanocarrier for drug delivery and targeting
Sherje Atul P., Jadhav Mrunal, Dravyakar Bhushan R., Kadam Darshana
International Journal of Pharmaceutics. 2018 548(1). p.707
Thiol–epoxy ‘click’ polymerization: efficient construction of reactive and functional polymers
Brändle Andreas, Khan Anzar
Polymer Chemistry. 2012 3(12). p.3224
A general synthetic strategy to prepare poly(ethylene glycol)-based multifunctional copolymers
De Swati, Stelzer Carol, Khan Anzar
Polymer Chemistry. 2012 3(9). p.2342
Thiol–yne and Thiol–ene “Click” Chemistry as a Tool for a Variety of Platinum Drug Delivery Carriers, from Statistical Copolymers to Crosslinked Micelles
Huynh Vien T., Chen Gaojian, Souza Paul de, Stenzel Martina H.
Biomacromolecules. 2011 12(5). p.1738
Bis‐hydrophilic and functional triblock terpolymers based on polyethers: Synthesis and self‐assembly in solution
Barthel Markus J., Babiuch Krzysztof, Rudolph Tobias, Vitz Jürgen, Hoeppener Stephanie, Gottschaldt Michael, Hager Martin D., Schacher Felix H., Schubert Ulrich S.
Journal of Polymer Science Part A: Polymer Chemistry. 2012 50(14). p.2914
Visible light photocatalysis with benzophenone for radical thiol-ene reactions
Singh Manjula, Yadav Arvind K., Yadav Lal Dhar S., Singh R.K.P.
Tetrahedron Letters. 2017 58(23). p.2206
Synthesis and Thermoresponsive Solution Properties of Poly[oligo(ethylene glycol) (meth)acrylamide]s: Biocompatible PEG Analogues
Chua Giles B. H., Roth Peter J., Duong Hien T. T., Davis Thomas P., Lowe Andrew B.
Macromolecules. 2012 45(3). p.1362
Recent developments in polypseudorotaxanes and polyrotaxanes
Arunachalam M., Gibson Harry W.
Progress in Polymer Science. 2014 39(6). p.1043

Committee on Publication Ethics


Abstract Export Citation Get Permission