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Synthesis and Pharmacological Evaluation of Novel Homocamptothecin-Dihydropyridine Derivative Conjugates as Potent Topoisomerase I Inhibitors

Ling-Jian Zhu A , Chun-Lin Zhuang A , Ning Lei B , Chun-Quan Sheng A C , Wei Guo A , Zhen-Yuan Miao A C , Wen-Feng Liu A , Jian-Zhong Yao A and Wan-Nian Zhang A C
+ Author Affiliations
- Author Affiliations

A School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, China.

B Department of Quality Assurance, Lian Yun Gang JARI Pharmaceutical Co., Ltd, 18 Zhenhua Road, Lianyungang 222100, China.

C Corresponding authors. Email: zhangwnk@hotmail.com; miaozhenyuan@hotmail.com; shengcq@hotmail.com

Australian Journal of Chemistry 64(10) 1390-1396 https://doi.org/10.1071/CH11091
Submitted: 25 February 2011  Accepted: 3 June 2011   Published: 23 August 2011



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