Australian Journal of Chemistry - an International Journal for Chemical Science publishes research papers from all fields of chemical science, with a focus on multidisciplinary chemistry and emerging areas of research. Read more about the journalMore
Editors-in-Chief: George Koutsantonis and John Wade
Publishing Model: Hybrid. Open Access options available.
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Novel matrine tricyclic derivatives have been designed and synthesised by a molecular fusion strategy. The most active compound ZM842 indicated potent inhibitory TGF-β transcriptional activity in a dose-dependent manner by downregulating collagen I and α-SMA protein. (Image credit: Yongchuang Wang.)
, Preeti Jain, Ankush Thakur, Sobhi M. Gomha and Swati Rani
Green synthesis is garnering global interest among researchers due to its distinctive characteristics and ecological advantages. Researchers are developing innovative ionic liquids (ILs) and enhancing their characteristics for application in green chemistry and synthesis, including environmentally friendly solvents and catalysts. They have been extensively used as green catalysts and solvent systems for the synthesis of many important heterocycles because of their distinctive features. (Image credit: Shubham Sharma.)
Levoglucosenone and the reduced analogue Cyrene are versatile chiral intermediates for synthesis, available from the cellulose fraction of biomass by acid-catalysed pyrolysis. An ethyl diazoacetate mediated ring expansion has been developed for Cyrene, and combination with a decarboxylation has resulted in homologated ring-systems. Some selected reactions for the first homologated ring-system were then investigated. (Image credit: Ben Greatrex.)
CH24163 Abstract | CH24163 Full Text | CH24163PDF (909 KB) | CH24163Supplementary Material (2 MB) Open Access Article
and Cui-Feng Yang
The Zn-mediated environmentally friendly and low-cost preparation of propiolonitriles using electrophilic cyanation of alkynyl bromides with N-cyano-N-phenyl-p-methylbenzenesulfonamide (NCTS) has been achieved here. In this new protocol, only low-toxicity, stable and easy-to-handle cyanating reagents, NCTS and inexpensive zinc dust were needed. (Image credit: Xiao Yun Chen.)
This review underscores the pivotal role of high-level composite wavefunction methods in revolutionising the construction of highly accurate thermochemical databases. These breakthroughs are critical for generating large-scale thermochemical datasets, which are crucial for advancing density functional theory (DFT) methods and improving machine-learning models to enable more reliable chemical predictions. (Image credit: A. Karton.)
CH24130 Abstract | CH24130 Full Text | CH24130PDF (1.3 MB) Open Access Article
, Weiping Chen, Yonggang Wu and Hongchi Zhao
Three novel mono BN substituted derivatives (PDI-BN1, PDI-BN2 and PDI-BN3) of symmetrical and asymmetrical perylene diimides were designed and efficiently synthesised using a concise synthetic strategy. These derivatives exhibited orange fluorescence, with their properties finely adjustable by integrating various fused aryl rings. Except for F− ions, these derivatives have shown no affinity for other anions. (Image credit: Feng Liu.)
, Jin Zhang, Linlin Zhong and Wenlong Xu
An amphiphilic peptide Fmoc-FFCKK-OH was designed to induce peptide self-assembly to form hydrogels by Au3+ ligand interaction. This study contributes to further understanding the role of AuNPs binding specifically to peptides in the formation of β-sheet-like aggregates and provides a research basis for AuNPs as amyloid aggregation regulator. (Image credit: Fangjie Liu.)
Na2FeO3 serves as a highly effective water-purifying agent, demonstrating superior performance when compared to ferrate(VI). This study focuses on the eco-friendly synthesis of Na2FeO3 crystals utilising sodium hypochlorite as the medium through a concentration method under depressurisation. The cost of synthesis is obviously lower than the traditional method. (Image credit: Haoda Guo.)
, Nisa V. Salim and Nishar Hameed
Functionalised polymers with antimicrobial properties have many applications as fouling-resistant materials in the maritime sector. Two polymer-based fabrication systems – one using a cast epoxy resin and the other employing stereolithography to produce polyurethane-based designs – were both used to produce structures incorporating dispersed copper thiocyanate for testing and evaluation as fouling-resistant materials. (Image credit: Richard Piola and Dominic Hare.)
CH24162 Abstract | CH24162 Full Text | CH24162PDF (3.7 MB) Open Access Article
, Eloah P. Ávila and Cleber P. A. Anconi
The inclusion process of clomiphene into β-cyclodextrin was investigated using various molecular modelling techniques, including static quantum computational (QC) methods, molecular dynamics (MD) and sequential QC/MD approaches. The calculated association constant showed good agreement with the experimental data , reflecting contributions from both multi-equilibrium processes and the fixed composition of the isomeric mixture. These results enhance understanding of the inclusion process and propose new methodological approaches for future research. (Image credit: Hélio F. Dos Santos.)
Theoretical calculations on the hydrogen evolution process by [FeFe]-hydrogenases-inspired molecular catalysts were linked with experimental catalytic performance to reveal their possible reaction mechanism. The theoretical data exhibited a good match with the experimental overpotential data, with a R2 of 0.592. (Image credit: Siyao Qiu.)
CH24137 Abstract | CH24137 Full Text | CH24137PDF (1.9 MB) | CH24137Supplementary Material (894 KB) Open Access Article
This review summarises the applications of hydroxamic acids in medicinal chemistry, mineral flotation, metal–organic frameworks (MOFs), remediation of metal contamination and more, and introduces related synthesis strategies including microwave, continuous flow reactor, solid-phase and enzymatic syntheses as supplements to classical synthetic methods. (Image credit: Li Yao.)
, Jagannadham Vandanapu and Adam A Skelton
There are innumerable instances of series conforming to linear free energy relationships (LFERs) in the literature and appreciable numbers of examples of non-conformity. It is extremely rare or maybe we are the first to report conformity and non-conformity of Hammett’s relationship (LFER) in the same system, the para-substituted phenyl pentazoles. This rarity and a plausible rationale are discussed. This research article requires a good understanding of Hammett’s relationship (LFER), harmonic oscillator model aromaticity (HOMA index) and bond length alternation (BLA). (Image credit: Sanjeev Rachuru.)
, Nirmal Parajuli, Prabhat Neupane, Manila Poudel , Timila Shrestha, Samjhana Bharati, Binita Maharjan, Bishnu Marasini and
Jhashanath Adhikari Subin
, Beau Allen, Andrew P. Montgomery , Jonathan J. Danon , Michael Kassiou
, Stuart C. Thickett , Rebecca O. Fuller
, Nisa V. Salim, Nishar Hameed
, Pritha Ghosh, Minghao Shang, Sauhta Siryer, Santhanalaxmi Kumaresan, Bishvanwesha Panda, Lani J. Davies, Upamali Somathilake, Abhishek P. Patel, Christoph Nitsche
, Gregory K. Pierens , James J. De Voss , Mary J. Garson
, Shannon Thoonen , Carol Hua
, Vishwanath Zunjar, Rahul R. Bagul
, Cui-Feng Yang
, Weiping Chen, Yonggang Wu, Hongchi Zhao
Beckwith Reviews honour the memory of Professor Athelstan (Athel) L. J. Beckwith, a remarkable man and an outstanding chemist. These invited reviews advance knowledge in current key areas of research in chemistry.
Last Updated: 17 Mar 2025
This collection presents papers submitted by 2023–24 Australian Academy of Science and Royal Australian Chemical Institute Award winners.
All papers in this collection are Open Access and the foreword by the Guest Editor, Curt Wentrup of the School of Chemistry and Molecular Biosciences at The University of Queensland, is free to read.
Last Updated: 10 Oct 2024
Primer Reviews are concise, authoritative overviews of important contemporary topics in the chemical sciences. They should appeal to advanced undergraduates, the general research chemist who is new to the field, as well as the expert. They provide a solid introduction to the development of a subject, the latest breakthrough results and their implications for the wider scientific community.
Last Updated: 12 Sep 2024
Cornforth Reviews honour the memory of Sir John Warcup Cornforth (usually known as Kappa to friends and colleagues). These invited reviews advance knowledge in current key areas of research in chemistry.
Last Updated: 22 Aug 2024
Australian Journal of Chemistry is approaching its eighth decade of publishing key work across many spheres of chemistry, both national and international. As the current co-editors-in-chief, we are delighted to introduce this collection that highlights a selection of the finest recent articles in medicinal chemistry. We are proud to also highlight the significant contributions to medicinal chemistry research made by several outstanding women researchers.
Collection Editors John Wade and George Koutsantonis
Last Updated: 01 Oct 2020
This collection reflects the breadth and quality of science published in the Australian Journal of Chemistry by Australian scientists over the last seven decades. Papers were selected based on hard data (citations and downloads), but we also chose papers that reflect other criteria, such as landmarks in important aspects of chemical science; recognition of an influential individual; gender diversity; and simply to reflect the breadth of the journal’s output.
Last Updated: 07 Feb 2019
Australian Journal of Chemistry is proud to have published the works of a number of Nobel prize winners of chemistry. This collection brings together the articles authored by these Nobel prize winners.
Last Updated: 01 Nov 2012
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