Australian Journal of Chemistry
Volume 64 Number 10 2011
CH11177Ion Translocation in Artificial Molecule-based Systems Induced by Light, Electrons, or Chemicals
Controlled ion and molecule transfer, the basis for many natural processes, is starting to be harnessed in a range of rudimentary supramolecular systems using a range of stimuli. An overview of biocompatible and purely artificial molecule-based systems employing intra- and intermolecular transfer processes is presented.
CH11184Recent Highlights in the use of Lanthanide-directed Synthesis of Novel Supramolecular (Luminescent) Self-assembly Structures such as Coordination Bundles, Helicates and Sensors
The use of lanthanide ion-directed synthesis in the formation of supramolecular self-assembly structures is described, focussing on recent examples from the literature.
CH11073 Cyclizations using Selenium Chemistry for Substituted 3-Hydroxypiperidines and 3-Hydroxypyrrolidines
Selenium-induced cyclization of 4-hydroxy-5-pentenylamines and 5-hydroxy-6-hexenylamines occurs with regio- and stereo-selectivity. Substituted pyrrolidines and piperidines are then afforded by oxidation of the SeII intermediate to SeVI and subsequent substitution with nucleophiles.
Three new morphine-based compounds containing arginyl and tetra-arginyl substitutents have been prepared. All had relatively high affinity for opoid receptors and the tetraarginyl compound showed some promise as an analgesic. None of the molecules showed transdermal activity.
CH10431Three Novel Polymeric CoII/CuII Complexes Assembled from 5-Nitro-1,2,3-benzenetricarboxylate and 4,4'-Bipyridine: Syntheses, Crystal Structures, and Magnetic Properties
Three new coordination compounds of CoII/CuII with 5-nitro-1,2,3-benzenetricarboxylate (O2N-btcH3) and 4,4′-bipyridyl ligands were synthesized and crystallographically characterized. It is found that these complexes are constructed by bi-/tri-nuclear secondary building units (SBUs) and exhibit intriguing 2D or 3D topological networks.
CH11095 Structural Chemistry of [MX2(bipy)] (M = Pd, Pt; X = Cl, Br, I): the Yellow Polymorph of Dichlorido(2,2'-bipyridine)platinum(II) and Diiodido(2,2'-bipyridine)palladium(II), and Overview of this System
Synchrotron data for the yellow polymorph of PtCl2(bipy) and PdI2(bipy) allow determination of crystal structures, and a comparison of structural chemistry for the series MX2(bipy) (M = Pd, Pt; X = Cl, Br, I) with nine structures distributed over five space groups.
Typical POCl3 contains predominantly 16O; consequently the reaction of POCl3 with water that is highly enriched in 18O produces predominantly five 16,18O isotope analogues of H3PO4. The proportions of the corresponding 16,18O isotope analogues of [H2PO4]–, estimated by electrospray ionization mass spectrometry, show that the O from POCl3 and H2O mix randomly into H3PO4.
CH10263 2-Chloro-2,2-difluoracetamide (ClF2CC(O)NH2). Thermal Decomposition, Vapour Infrared, Mass Spectrometry, Low-temperature NMR, and Theoretical Studies. Solvent Effects on Conformational Preferences
A new series of studies was carried out for 2-chloro-2,2-difluoroacetamide (CDFA) in order to complete its characterization. Following this goal, thermal decomposition, vapour FT-IR, mass spectrometry, low-temperature NMR, and theoretical studies were performed. Also, conformational analysis was carried out both experimentally and theoretically for CDFA in protic and aprotic solvents.
CH10459 A Series of 2D and 3D Novel Lanthanide Complexes Constructed from Squarate C4O42–: Syntheses, Structures, Magnetic Properties, and Near-infrared Emission Properties
A series of 2D and 3D novel lanthanide complexes constructed from squarate C4O42– are prepared. Three new coordination modes, a bidentate/monodentate μ3 and two bidentate/monodentate μ4 coordination modes, are first reported. In addition, the variable-temperature magnetic properties, the solid-state near-infrared (NIR) luminescence spectra, and the thermogravimetric analyses are discussed.
CH11067 A New Synthetic Protocol for One-Pot Preparations of 5-Halo-1,4-disubstituted-1,2,3-triazoles
CuX-oxidant systems are studied for the preparation of 5-halo-1,4-disubstituted-1,2,3-triazoles by the combination of a CuAAC reaction and an oxidative halogenation reaction in one pot, and an efficient method for the preparation of these kind of compounds under mild conditions is developed.
CH11091 Synthesis and Pharmacological Evaluation of Novel Homocamptothecin-Dihydropyridine Derivative Conjugates as Potent Topoisomerase I Inhibitors
A series of novel homocamptothecin derivatives conjugating with dihydropyridine derivates were designed and synthesized based on a semisynthetic route. Most of the synthesized compounds exhibited good cytotoxic activity on tumour cell lines and showed superior Topo I inhibition activity comparable to or higher than camptothecins.
CH11079 Nitrile Oxide 1,3-Dipolar Cycloaddition by Dehydration of Nitromethane Derivatives Under Continuous Flow Conditions
Aliphatic nitrile oxides were generated in situ, by dehydration of terminal nitro compounds, and reacted with dipolarophiles using continuous flow techniques to afford substituted isoxazolines. In-line scavenger cartridges conveniently removed by-products and unreacted reagents to give almost pure crude products.
Constructive embedding is developed so that one can elaborate new polyenes that have known embeddability.
CH11051Molecular Photodiode and Two-channel Optoelectronic Demultiplexer based on the Fullerene-porphyrin Tetrad
Porphyrin-fullerene tetrad with Langmuir–Blodget films on Au substrates shows diode-like behaviour. Photocurrent polarity can be switched from cathodic to anodic and vice versa by changing the subtrate potential. Photoelectrochemical properties of this system were used to mimic a two-channel demultiplexer.