Australian Journal of Chemistry Australian Journal of Chemistry Society
An international journal for chemical science

Isopalinurin: a Mild Protein Phosphatase Inhibitor From a Southern Australian Marine Sponge, Dysidea sp.

L Murray, ATR Sim, JAP Rostas and RJ Capon

Australian Journal of Chemistry 46(8) 1291 - 1294
Published: 1993


A new sesterterpene tetronic acid, isopalinurin (1), has been isolated from an Australian marine sponge, Dysidea sp., collected in Bass Strait. Isopalinurin (1) was identified as the agent responsible for the antibiotic activity and protein phosphatase inhibitory properties exhibited by the crude ethanol extract, and its structure was secured by detailed spectroscopic analysis.

© CSIRO 1993

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