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Polarity Inversion Catalysis by the 1,4-Addition of N-Heterocyclic Carbenes

Xuan B. Nguyen A , Yuji Nakano A and David W. Lupton https://orcid.org/0000-0002-0958-4298 A B
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A School of Chemistry, Monash University, Clayton, Vic. 3800, Australia.

B Corresponding author. Email: david.lupton@monash.edu




Xuan B. Nguyen completed a Bachelor of Biotechnology majoring in chemistry and pharmacology before graduating with Honours (first class) in chemistry under the supervision of Professor David W. Lupton at Monash University in 2017. In 2018, he commenced studies towards a Doctorate of Philosophy in the same group. His studies are focused on the discovery of polarity reversal of conjugate acceptors enabled by NHC catalysis.



Yuji Nakano completed a Bachelor of Science (Science Scholar Program) at Monash University in 2012 and a Ph.D. in 2017 at Monash University under the supervision of Professor David W. Lupton, where he worked on enantioselective N-heterocyclic carbene catalysis. From there, Yuji moved to Princeton University as an Endeavour Postdoctoral Fellow to conduct post-doctoral research with Professor Todd K. Hyster, investigating photoenzymatic catalyzed processes. In mid-2019, Yuji returned to Melbourne and took up a position as a post-doctoral fellow with Professor Jonathan B. Baell, where he is undertaking medicinal chemistry research at the Monash Institute of Pharmaceutical Sciences.



David W. Lupton graduated with a Bachelor of Science (Honours, first class) in 2001 (University of Adelaide) before being awarded a Doctorate of Philosophy for studies under the supervision of Professor Martin G. Banwell (Australian National University) in 2005. Dr Lupton then undertook a post-doctoral fellowship with Professor Barry M. Trost (Stanford University) as a Sir Keith Murdoch fellow of the American Australian Association. In 2007, he returned to Australia to take up an academic appointment at Monash University in Melbourne, receiving an Australian Research Council Future Fellowship in 2011, and promotion to Professor in 2018. In 2010, he received the Athel Beckwith Lectureship of the Royal Australian Chemical Institute (RACI) while in 2013 he received the Rennie Medal of the RACI. Studies under David’s supervision are focused on the capacity of catalysis to enable discoveries in chemical synthesis.

Australian Journal of Chemistry 73(1) 1-8 https://doi.org/10.1071/CH19550
Submitted: 25 October 2019  Accepted: 27 November 2019   Published: 3 February 2020



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