This review summarizes the formation, structure, stability and reactions of aryliodonium zwitterions of closo-borate anions. The zwitterions are formed by regioselective aryliodination of closo-borates with ArI^II reagents and undergo efficient reactions with nucleophiles. Therefore, this tandem of reactions represents an effective regioselective activation of the B–H bonds in closo-borates towards nucleophilic substitution. (Image credit: Piotr Kaszyński.)

The compounds present in Psidium guajava L. were evaluated against three different proteins (PDB ID: 4A79, 7E3H, 7F61) associated with the regulation of neurodegenerative diseases. Using a computational approach, these compounds were tested for their capability to inhibit the proteins. The resultssupport the potential of P. guajava compounds in managing neurodegenerative disorders. (Image credit: the authors.)